Most Effective Anti-Anxiety Dog
Supplement in 2022

Discover what to look out for when giving your dog anxiety suplement and which are worth buying

by Gill Ritcher updated on

Gill is our resident pet health and nutrition expert who recently retired from a 14-year career in veterinary teaching to pursue writing and researching.

Importance of Anxiety Prevention

It’s immensely hard for a caring pet owner to witness their dog experiencing anxiety. Preventing anxiety from snowballing into destructive, aggressive or difficult behaviors is vital.


Anxiety in dogs comes in several different forms, such as fear-based (such as car rides, new environments or loud noises), separation anxiety (the inability to calm themselves when left alone), and age-based anxiety which worsens as they get older. Knowing how to prevent anxiety and alleviate your dog’s stress is a key part of their wellbeing.


Nature provides us with the perfect ingredients for soothing and easing our four-legged friends.

Symptoms of Anxiety in Dogs

Your dog is a unique being, so you will need to learn the signs of anxiety in your dog, which may be different from another. However, there are some common symptoms:

  • Destructive behavior
  • Aggression
  • Panting and drooling
  • Urinating/defecating inside
  • Low mood/depression
  • Excessive barking
  • Growling
  • Restlessness and/or pacing
  • Compulsive behaviors
  • Unsettled stomach, nausea and vomiting

Benefits of Chamomile Flower Powder & L-Tryptophan

Choosing natural ingredients with scientifically-proven benefits ensures you choose the right anti-anxiety supplement for your dog, to get him happy and content once more. Chamomile Flower Powder and L-Tryptophan have been shown to be enormously beneficial for anxious dogs:

High Quality Dog Anxiety Suplement:

Chamomile is known for being a natural gentle sedative.

Alleviates stress and promotes calm.

L-Tryptophan is converted into the feel good hormone, serotonin.

Serotonin brings a sense of ease, and aids sleep.

Works to reduce aggression.

What Ingredients to Look for in an Anxiety-Relief Supplement

It can be confusing to know what to give your dog to help alleviate their anxiety, and to help prevent it. We recommend choosing natural supplements with the following evidence-based ingredients:

Chamomile Flower Powder

To naturally relieve the feelings of stress and anxiety.

L-Tryptophan

To promote serotonin production to soothe and facilitate good sleep.

Ginger Root Powder

To calm an anxious stomach and alleviate nausea.

Passion Flower Powder

To help reduce anxiety and bring a feeling of ease.

Definitive Checklist for Canine Anxiety-Relief Supplements

When choosing an anxiety-relief supplement for your dog, make sure to look for:

L-Tryptophan

L-Tryptophan is an essential ingredient as it helps the dog’s own system work more harmoniously to reduce anxiety.

Serving Sizes

Natural ingredients are less likely to cause high levels of drowsiness compared to medications, but you still need to know the right amount to give based on size.

Money-Back Guarantee

Be sure that you’re choosing a reliable and responsible brand by checking for a money-back guarantee.

Tasty Chew

Anxious dogs do better with a tasty chew, rather than the additional stress of a pill.

All-Natural

Choose a supplement which uses all-natural ingredients to give your dog the best.

How We Evaluated The Top 5

Our product comparisons go through a very strict review, of both internal expertise as well as external research such as product reviews and professional opinion. We assess a score based on each of the following criteria to determine the best products:

Effectiveness

Ingredients

Value for Money

Customer Service

Overall Ranking
Overall Ranking
A+
Grade
A+
Overall Ranking

Pros

Contains Passion Flower
Contains Chamomile
High Dose of L-Trypophan
Made in USA
Soft Chew Form
Moneyback Guarantee
Recommended by Vets

Cons

Only Available Online
Sometimes Out of Stock
Express Delivery Is Extra

The Bottom Line

Of every dog probiotic supplement we tested, Pawfy's Calming Soft Chews provide the best all round calming supplement, by combining high potency dosages of good quality ingredients. Pawfy's Calming Soft Chews contain Passion Flower andChamomile to give a powerful calming effect. In addition, it contains Ginger Root which helps ease dogs stomachs when they are anxious or stressed.

Most importantly, it has a high dose of L-Tryptophan which helps reduce aggression and stress in dogs. This supplement is contained in a flavoured soft chew which is helpful for picky dogs. Other benefits of this product include a moneyback guarantee and free shipping.

2. Calm with Melatonin

by Waggedy
Overall Ranking
Overall Ranking
B+
Grade
B+
Overall Ranking

Pros

Contains Chamomile

Made in USA

Free Shipping

Cons

Contains Melatonin (Side Effects)

Low Dosages of Chamomile

Expensive

The Bottom Line

Waggedy's supplements come second, as their ingredients are natural and it contains doses of chamomile. However, it's dosages are not as potent and therefore you require a larger serving size. In addition, it contains Melatonin which can be unsafe for dogs in high doses and it's inclusion can cause many side effects. Side effects include drowsiness, sickness, itching and an increased heart rate. We do not recommend giving your dog melatonin and would advise opting for an all natural supplement that contains L-Trypophan instead.

3. Every Dog's Calming Aid

by NexPaw
Overall Ranking
Overall Ranking
B
Grade
B
Overall Ranking

Pros

Made in USA

Free Shipping

Cons

Contains Melatonin (Side Effects)

Lacks L-Trypophan

Bad Customer Reviews

The Bottom Line

This calming aid has a poor ingredient mix, but it is all natural and made in the USA which is a plus. The main concern with this is the inclusion of melatonin and the side effects that could affect dogs as a result. Furthermore, poor customer reviews on the internet demonstrate that the effectiveness of this product is questionable.

4. Calming Chews

by Supps For Pets
Overall Ranking
Overall Ranking
B-
Grade
B-
Overall Ranking

Pros

Contains Passion Flower

Contains Ginger Root

Made in USA

Cons

Contains Melatonin (Side Effects)

Lacks Chamomile

Slow Shipping

The Bottom Line

These calming chews come in flavoured soft chew form which is great for ensuring your dog takes them. However, again the inclusion of melatonin could be dangerous at worst and cause side effects at best for your dog. Furthermore, this product lacks chamomile which is one of the best ingredients for calming and de-stressing your dog.

5. Max Hemp Calming Treats

by Mighty Petz
Overall Ranking
Overall Ranking
C
Grade
C
Overall Ranking

Pros

Contains Hemp

Made in USA

Free Shipping

Cons

Low Dosages

Harmful Inactive Ingredients

Slow Shipping

The Bottom Line

The inclusion of hemp in this product makes it a good contender, but it falls short on the harmful inactive ingredients. Inactive ingredients are those in small doses and so while it is not dangerous for your dog, there are known side effects of the ingredients whcih are used in this product. Furthermore, customer complaints of slow shipping and poor demonstrable results lower the ranking of this calming aid.

Overall, Pawfy's Calming Soft Chew Supplement provides the best bang for your buck and contains scientifically proven ingredients to relax your pup. These supplements are recommended for any owner of a dog that suffers from separation anxiety, general anxiety, agitation or stress.

Made
in U.S.A

Free
Shipping

Money-Back
Guarantee