Best Anxiety Relief For Dogs in 2025
Discover what to look out for when trying to support your dog's anxiety.
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- Top 5
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Updated on
Gill is our resident pet health and nutrition expert who recently retired from a 14-year career in veterinary teaching to pursue writing and researching.
Importance of Anxiety Prevention
Did you know? Anxiety is one of the most common conditions in dogs. Generally caused by separation, stressful events, travelling or even a new family member, anxiety can cause real havoc to your dog.
Anxiety in dogs can cause real psychological and physical issues in your dog. As it effects various chemicals in their brain, the secondary health issues of anxiety can be severe. Not to mention, it is downright stressful for both the dog and their owner. This is why early prevention is key and the sooner the better when it comes to relieving your dog's anxiety.
Luckily, with the right anxiety relief supplement, your dog can see huge signs of improvement in just 2-3 weeks. Read on to discover our recommended Top 5 Anxiety Relief Products.
Symptoms of Anxiety in Dogs
Your dog is a unique being, so you will need to learn the signs of anxiety in your dog, which may be different from another. However, there are some common symptoms:
- Destructive behavior
- Aggression & biting
- Panting and drooling
- Urinating/defecating inside
- Low mood/depression
- Excessive barking
- Growling
- Restlessness and/or pacing
- Compulsive behaviors
- Unsettled stomach, nausea and vomiting
Benefits of Anxiety-Relief Supplements
Extensive research has shown many benefits of key natural ingredients, which can reduce anxiety or stress without the drowsy side effects of medications.
High Quality Anti-Anxiety Supplements Can:
- Support Anxiety in Dogs
- Help With Separation Anxiety
- Manage Stress & Aggression
- Support Sleep, Mood & Energy
- Reduce Over-Excitedness & Barking
- Relax Without Drowsy Side-Effects
What To Look For In Anti-Anxiety Supplements
It can be confusing to know what to give your dog to help alleviate their anxiety, and to help prevent it. We recommend choosing natural supplements with the following evidence-based ingredients:
Chamomile Flower Powder To naturally relieve the feelings of stress and anxiety.
L-Tryptophan To support serotonin production and improve energy & sleep.
Ginger Root Powder To reduce upset stomachs, nausea and digestive issues.
Passion Flower Powder To help reduce anxiety and bring a feeling of ease.
Our Product Checklist For Anxiety Relief
These are some signs of a good quality product and may improve your chances of seeing results:
CloseOpen the ChecklistL-Tryptophan
L-Tryptophan is an important ingredient as it helps the dog’s own system work more harmoniously to reduce anxiety.
Money-Back Guarantee
Brands with a 30 day money back guarantee commonly have higher quality products and lower risk.
Chew Form
When stressed, it may be difficult to give dogs powders or pills. So it may help to find a product in chew or treat form.
All-Natural
Choose a supplement which uses all-natural ingredients to give your dog the best.
How We Evaluated the Top 5
Effectiveness
Ingredients
Value for Money
Customer Service
Top 5 Anxiety Relief For Dogs in 2025
A+
OVERALL GRADE
TOTAL RANKING
Pros
High Dose of L-Tryptophan
Contains Passion Flower
Includes Chamomile
Made in USA from US & Global Ingredients
Soft Chew Form
30 Day Money Back Guarantee
Cons
Only Available Online or Amazon Only Available Online
Sometimes Out of Stock
The Bottom Line
Of the anxiety relief products we’ve reviewed for dogs, Pawfy’s Calming Soft Chews has come out as e the strongest contender for easing your dog's anxiety.
By combining potent doses of natural, high quality ingredients such as L-Tryptophan and Passion flower, their formula is design to help relax dogs without any drowsy side effects. By combining these ingredients with Chamomile, these chews can support anxiety, stress, over-excitement or aggression in dogs.
With the inclusion of Ginger Root Powder, they also have the added benefit of easing upset stomachs, nausea, motion sickness and as a result may also help dogs during travel or other stressful events.
It is clear that Pawfy has one of the most robust anti-anxiety and calming formulas on the market. Equally important is the fact that they are Made in the USA from US & Global Ingredients, come with a 30 Day Money Back Guarantee and Free Shipping, which allows readers to try them risk-free.
Overall, we have rated Pawfy as having the best Calming supplement on the market in 2025.
Calm with Melatonin
by Waggedy
B+
OVERALL GRADE

TOTAL RANKING
Pros
Contains Chamomile
Made in USA
Free Shipping
Cons
Contains Melatonin (Side Effects)
Low Dosages of Chamomile
Expensive
The Bottom Line
Waggedy's supplements come second, as their ingredients are natural and it contains doses of chamomile. However, it's dosages are not as potent and therefore you require a larger serving size. In addition, it contains Melatonin which can be unsafe for dogs in high doses and it's inclusion can cause many side effects. Side effects include drowsiness, sickness, itching and an increased heart rate. We do not recommend giving your dog melatonin and would advise opting for an all natural supplement that contains L-Trypophan instead.
* Results and rankings are based on our subjective opinion and do not necessarily reflect typical results from the use of these products. We receive compensation from "Sponsored" products which may influence their position. Please visit product website for more information.Every Dog's Calming Aid
by NexPaw
B
OVERALL GRADE

TOTAL RANKING
Pros
Made in USA
Free Shipping
Cons
Contains Melatonin (Side Effects)
Lacks L-Trypophan
Bad Customer Reviews
The Bottom Line
This calming aid has a poor ingredient mix, but it is all natural and made in the USA which is a plus. The main concern with this is the inclusion of melatonin and the side effects that could affect dogs as a result. Furthermore, poor customer reviews on the internet demonstrate that the effectiveness of this product is questionable.
* Results and rankings are based on our subjective opinion and do not necessarily reflect typical results from the use of these products. We receive compensation from "Sponsored" products which may influence their position. Please visit product website for more information.Calming Chews
by Supps For Pets
C
OVERALL GRADE

TOTAL RANKING
Pros
Contains Passion Flower
Contains Ginger Root
Made in USA
Cons
Contains Melatonin (Side Effects)
Lacks Chamomile
Slow Shipping
The Bottom Line
These calming chews come in flavoured soft chew form which is great for ensuring your dog takes them. However, again the inclusion of melatonin could be dangerous at worst and cause side effects at best for your dog. Furthermore, this product lacks chamomile which is one of the best ingredients for calming and de-stressing your dog.
* Results and rankings are based on our subjective opinion and do not necessarily reflect typical results from the use of these products. We receive compensation from "Sponsored" products which may influence their position. Please visit product website for more information.Calming Treats
by Inner Paw
D+
OVERALL GRADE

TOTAL RANKING
Pros
Made in USA
Contains Passion Flower
Free Shipping
Cons
Low Dosages
Harmful Inactive Ingredients
Slow Shipping
The Bottom Line
The inclusion of passion flower in this product makes it a good contender, but it falls short on the harmful inactive ingredients. Inactive ingredients are those in small doses and so while it is not dangerous for your dog, there are known side effects of the ingredients whcih are used in this product. Furthermore, customer complaints of slow shipping and poor demonstrable results lower the ranking of this calming aid.
* Results and rankings are based on our subjective opinion and do not necessarily reflect typical results from the use of these products. We receive compensation from "Sponsored" products which may influence their position. Please visit product website for more information.Our
Recommendation
Top Dog Calming Suplement of 2025
Sponsored
This is a sponsored recommendation by our affiliated partner.

- Efectiveness A+
- Ingredients A+
- Value for Money A+
- Customer Service A+
Overall, Pawfy's Calming Soft Chew Supplement provides the best bang for your buck and contains scientifically proven ingredients to relax your pup. These supplements are recommended for any owner of a dog that suffers from separation anxiety, general anxiety, agitation or stress.